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Trifexis Kills Dogs!

Holiday

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It's up to people to make their own determination. For me, I'm not convinced by anecdotal evidence--I'd need to see a reputable study that explains the issue in scientific terms. And, since Collies and Shepherds cannot take any Ivermectin or related heartworm preventive without serious and well documented risk, that pretty much leaves Trifexis, which my Alice is on, and she's doing just fine. :)
 

sthiele

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That's not weird at all!! Sorry, what I really meant was if you can get Sentinel - you should be able to get Interceptor. Is it still on back-order where you live?
Interceptor is no longer in production, at least in the US. It was phased out after the backorder issues and they only offer Sentinel now, which is what I've been using for over a year now.
 

roxynoodle

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It's up to people to make their own determination. For me, I'm not convinced by anecdotal evidence--I'd need to see a reputable study that explains the issue in scientific terms. And, since Collies and Shepherds cannot take any Ivermectin or related heartworm preventive without serious and well documented risk, that pretty much leaves Trifexis, which my Alice is on, and she's doing just fine. :)

Agree. When it comes to medical issues I want to see the information from reputable sources and written by experts in that field.
 

Love My Zons

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I had Vets argue with me over the Invermectin issue with my Shelties (collie related breeds sensitivity to it) and that one Vet was like "who are you going to believe the Vet or the breeder?" I always went with what my breeder said, no Invermectin! :idea:
 

DWRVT

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Darby's reaction was not anecdotal evidence - he's my dog and I saw it with my own eyes and felt his suffering with my own heart :( The reactions that the specialist I work for are real cases of dogs he has treated after Trifexis use. I agree that everyone needs to make their own decision and that not all dogs will have bad reactions to this medication but I truly believe that the possible side effects of such medications should be honestly relayed and right now, the makers of Trifexis are not doing so.
 

Yoshi&Reza

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That's not weird at all!! Sorry, what I really meant was if you can get Sentinel - you should be able to get Interceptor. Is it still on back-order where you live?
My vet hasn't had it for over a year and their website says Interceptor is no longer being made but Sentinel is available.
 

Yoshi&Reza

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Interceptor is no longer in production, at least in the US. It was phased out after the backorder issues and they only offer Sentinel now, which is what I've been using for over a year now.
Didn't see this post! Sorry!
 

Yoshi

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Darby's reaction was not anecdotal evidence - he's my dog and I saw it with my own eyes and felt his suffering with my own heart :( The reactions that the specialist I work for are real cases of dogs he has treated after Trifexis use. I agree that everyone needs to make their own decision and that not all dogs will have bad reactions to this medication but I truly believe that the possible side effects of such medications should be honestly relayed and right now, the makers of Trifexis are not doing so.
I'm so sorry about your dog, but yes - it is an example of anecdotal evidence. Its evidence based on personal accounts. It only becomes more than anecdotal when further research is conducted and it is scientifically proven that XYZ was the cause. Just because its anecdotal does not mean its automatically wrong or incorrect, just not scientifically backed.
 

Holiday

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Yeah, an anecdote is a short personal story. And, short personal stories do not prove a larger pattern of cause and effect. (If they did, then we could believe in, say, alien abductions. Lots of people claim to have experienced that. But, I'm not holding my breath that they'll be able to produce a space ship anytime soon. :) And, even if your dog did have some kind of bad reaction to the product, it would likely be statistically insignificant, and so, it does not mean that my dog will have a bad reaction too. For instance, a woman in my state might say, "hey, I won the lottery!" And she did. But, that doesn't mean that if I went to 7 Eleven and bought a ticket that I would win too just because she did. Good luck or bad--her story does not make a statistically significant pattern). So, I will rely on the scientific evidence available to make decisions regarding my pets' health care. Everything I've read about Trifexis (or heard from my vet) indicates that it is currently the best choice overall for collies and shepherds.
 

Bailey

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I just don't see the point in taking the risk. I won't experiment with this stuff on my dog, even if he has been on it a long time.

It takes quite some time for more than anecdotal evidence to be available, because lots of med companies are in it for the $$$ and as long as there are enough people still buying the product and they have a way around not being blamed for these dogs exhibiting symptoms of being poisoned then confirmed reports/scientific studies won't be available.
 

Holiday

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I just don't see the point in taking the risk. I won't experiment with this stuff on my dog, even if he has been on it a long time.

It takes quite some time for more than anecdotal evidence to be available, because lots of med companies are in it for the $$$ and as long as there are enough people still buying the product and they have a way around not being blamed for these dogs exhibiting symptoms of being poisoned then confirmed reports/scientific studies won't be available.


Companies are in it for the money, which is why most of the time, they do significant testing in advance and often will not put a truly unsafe product on the market because it will seriously hurt their public image and profit margin. Also, vets have seen this product on the market for a while, so the overall clinical data is there. Of course, there are always going to be individuals who don't do well on a particular drug. But, what makes sense is a cost/benefit analysis in the case of your pet. In my pet's case, she has few options aside from Trifexis, since no Ivermectin or related drug is truly safe for her (well, according to my research, as a GSD, she has a 33% chance of Ivermectin being deadly, and I could have her genetically tested to find out what her individual risk truly is, but it's just much easier to avoid those products). Heart worms are a big health threat--she needs something that will protect her from that known risk. Cost: small risk supported by a few scare stories on the 'net. Benefit: protection from heartworms that will kill my dog. Conclusion: no brainer.

I'm not saying I'd never change my opinion if presented with more compelling evidence, but for now, this is my take.
 

waterfaller1

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I called my vet and asked about the comfortis we use. She said they are fully aware of what people are writing about it. She said it has been tested on thousands, and 1% has issue. We used to use advantage,but it became ineffective. Florida is bad for fleas.
 

Buddy Boy Drake

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Comfortis is a great flea control for dogs and cats. It contains an organic bacterium called Spinosad. I use this on my dog every month. I like it best because it's not a Systemic ,It does not travel threw your animals blood stream like advantage does. Advantage contains imidacloprid that travels thru the blood line of your pet. Imidacloprid is made from tobacco (Nicotine). We all know the side affects of Nicotine.
 

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I called my vet and asked about the comfortis we use. She said they are fully aware of what people are writing about it. She said it has been tested on thousands, and 1% has issue. We used to use advantage,but it became ineffective. Florida is bad for fleas.
You aren't kidding. I thought Kansas was bad for fleas and ticks but I was sorely mistaken. Being right next to a small forest just makes it that much easier to pick up unwanted "guests".
 

Hallie

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Why buy heartguard or any other ivermectin based preventative?

I went out and got a big bottle of ivermectin and my vet told me how much to give my dog. It's seriously the cheapest way, and it's just as effective as heartguard and several others. Your not paying for the medicine. You're paying for the packaging and the company's advertising.


And the BEST for fleas (I work in the pet care industry) is hands down the Seresto flea collar. It last for 8 months, you just can't beat that! It's non invasive, doesn't smell like the drops, and doesn't make your dog throw up like oral medications can.
 
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